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Effect of CPT‐11 on Lipid Peroxide Level in Mouse Tissues

We examined the effects of CPT‐11 on lipid peroxide level and glutathione peroxidase (GSHpx) activity as indices of the toxicity of this antitumor agent in mouse and rat tissues. After CPT‐11 (100 mg/kg, i.p.) administration, the lipid peroxide level in the heart increased 1.5 fold (mice) and 1.3 fo...

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Bibliografiske detaljer
Udgivet i:Jpn J Cancer Res
Main Authors: Sadzuka, Yasuyuki, Hirota, Sadao
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 1997
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921459/
https://ncbi.nlm.nih.gov/pubmed/9247609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1997.tb00411.x
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