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Rare Occurrence of ras and p53 Gene Mutations in Mouse Stomach Tumors Induced by N–Methyl–N–nitrosourea

The incidence of point mutations of H–, K– and N–ras and p53 oncogenes in male BALB/c mouse stomach tumors induced with A(r)–methyl–A(r)–nitrosourea (MNU) was examined by direct sequencing and PCR single–strand conformation polymorphism (PCR–SSCP). A mutation of GGT to AGT at K–ras codon 12 was foun...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Furihata, Chie, Tatematsu, Masae, Saito, Masae, Ishida, Shizuka, Nakanishi, Hayao, Inada, Ken‐ichi, Tei, Hajime, Hattori, Masahira, Ito, Takashi, Sakaki, Yoshiyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921434/
https://ncbi.nlm.nih.gov/pubmed/9197527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1997.tb00390.x
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