Rare Occurrence of ras and p53 Gene Mutations in Mouse Stomach Tumors Induced by N–Methyl–N–nitrosourea

The incidence of point mutations of H–, K– and N–ras and p53 oncogenes in male BALB/c mouse stomach tumors induced with A(r)–methyl–A(r)–nitrosourea (MNU) was examined by direct sequencing and PCR single–strand conformation polymorphism (PCR–SSCP). A mutation of GGT to AGT at K–ras codon 12 was foun...

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Pubblicato in:Jpn J Cancer Res
Autori principali: Furihata, Chie, Tatematsu, Masae, Saito, Masae, Ishida, Shizuka, Nakanishi, Hayao, Inada, Ken‐ichi, Tei, Hajime, Hattori, Masahira, Ito, Takashi, Sakaki, Yoshiyuki
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 1997
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921434/
https://ncbi.nlm.nih.gov/pubmed/9197527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1997.tb00390.x
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