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Altered Expression of γ‐Glutamylcysteine Synthetase, Metallothionein and Topoisomerase I or II during Acquisition of Drug Resistance to Cisplatin in Human Ovarian Cancer Cells
This study was designed to elucidate the mechanisms of cisplatin (CDDP) resistance using two human ovarian cancer cell lines, KF and TYK, and two CDDP‐resistant lines, KFr and TYK/R, derived from the former lines. KFr and TYK/R showed about 3‐fold higher resistance to the cytotoxic effects of CDDP t...
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| Publicado no: | Jpn J Cancer Res |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5921366/ https://ncbi.nlm.nih.gov/pubmed/9119751 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1997.tb00368.x |
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