Promotion of Rat Hepatocarcinogenesis by Dimethylarsinic Acid: Association with Elevated Ornithine Decarboxylase Activity and Formation of 8‐Hydroxydeoxyguanosine in the Liver

Arsenicals are epidemiologicaUy significant chemicals in relation to induction of liver cancer in man. In the present study, we investigated the dose‐dependent promotion potential of dimethylarsinic acid (DMAA), a major metabolite of inorganic arsenicals in mammals, in a rat liver carcinogenesis mod...

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Pubblicato in:Jpn J Cancer Res
Autori principali: Wanibuchi, Hideki, Hori, Takaaki, Meenakshi, Vijayaraghavan, Ichihara, Toshio, Yamamoto, Shinji, Yano, Yoshihisa, Otani, Shuzo, Nakae, Dai, Konishi, Yoichi, Fukushima, Shoji
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 1997
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921341/
https://ncbi.nlm.nih.gov/pubmed/9473732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1997.tb00343.x
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