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p53 Gene Deficiency Does Not Enhance Instability of Mouse Minisatellites in Somatic Cells of Normal Tissues

The effect of p53‐deficiency on somatic mutation of minisatellites in normal tissues was examined using p53‐deficient (−/−) mice. In total, 248 mice consisting of three different genotypes, +/+, +/− and −/−, were obtained and DNA from their embryos was probed with two minisatellites, Pc‐1 and Pc‐2....

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Ohashi, Manabu, Hatakeyama, Katsuyoshi, Aizawa, Shinichi, Kominami, Ryo
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921163/
https://ncbi.nlm.nih.gov/pubmed/8698618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1996.tb00280.x
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