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Relationship between Cell‐killing Efficiency and Number of Platinum Atoms Binding to DNA, RNA, and Protein Molecules in HeLa Cells Treated with cis‐Diamine(glycolato)platinum(II)

HeLa S‐3 cells were treated with (195m)Pt‐radiolabeled cis‐diamine(glycolato)platinum(II) (254‐S) under various conditions, and the relationship between the lethal effect and the numbers of Pt atoms binding to DNA, RNA, and proteins was examined. The mean lethal concentrations for the cells treated...

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Опубликовано в: :Jpn J Cancer Res
Главные авторы: Akaboshi, Mitsuhiko, Kawai, Kenichi, Kinashi, Yuko, Masunaga, Shinichiro, Ono, Koji
Формат: Artigo
Язык:Inglês
Опубликовано: Blackwell Publishing Ltd 1996
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921063/
https://ncbi.nlm.nih.gov/pubmed/8609067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1996.tb03156.x
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