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Tropomyosin-1 promotes cancer cell apoptosis via the p53-mediated mitochondrial pathway in renal cell carcinoma

Tropomyosin-1 (TPM1), a widely expressed actin-binding protein, is downregulated in many tumors and associated with cancer progression. A previous study from our group suggested that TPM1 could be involved in renal cell carcinoma (RCC) apoptosis, but the mechanisms and details remained unknown. The...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Tang, Chao, Wang, Jin, Wei, Qi, Du, Yi-Peng, Qiu, He-Ping, Yang, Chao, Hou, Yu-Chuan
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921034/
https://ncbi.nlm.nih.gov/pubmed/29731872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2018.8204
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