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In vivo Anti‐tumor Efficacy of Polyethylene Glycol‐modified Tumor Necrosis Factor‐α against Tumor Necrosis Factor‐resistant Tumors
We previously reported that the optimally PEGylated tumor necrosis factor‐α (MPEG‐TNF‐α), in which 56% of the TNF‐α‐lysine amino groups were coupled with polyethylene glycol (PEG), had about 100‐fold greater anti‐tumor effect than native TNF‐α. Here, we assessed the usefulness of MPEG‐TNF‐α as a sys...
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| Udgivet i: | Jpn J Cancer Res |
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| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Blackwell Publishing Ltd
1996
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5920990/ https://ncbi.nlm.nih.gov/pubmed/8957067 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1996.tb03113.x |
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