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Inostamycin, an Inhibitor of P‐Glycoprotein Function, Interacts Specifically with Phosphatidylethanolamine
The mechanism of inostamycin action was further studied. When multidrug‐resistant KB‐C4 cells were preincubated with inostamycin for 30 min, the accumulation of [(3)H]vinblastine was increased for as long as 48 h thereafter. Inostamycin inhibited azidopine binding to P‐glycoprotein, even after KB pl...
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| Udgivet i: | Jpn J Cancer Res |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Blackwell Publishing Ltd
1995
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5920936/ https://ncbi.nlm.nih.gov/pubmed/7591966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1995.tb03099.x |
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