Platelets drive thrombus propagation in a hematocrit and glycoprotein VI dependent manner in an in vitro venous thrombosis model

OBJECTIVE: To measure the role of platelets and red blood cells (RBC) on thrombus propagation in an in vitro model of venous valvular stasis. APPROACH AND RESULTS: A microfluidic model with dimensional similarity to human venous valves consists of a sinus distal to a sudden expansion, where for suff...

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Vydáno v:Arterioscler Thromb Vasc Biol
Hlavní autoři: Lehmann, Marcus, Schoeman, Rogier M., Krohl, Patrick J., Wallbank, Alison M., Samaniuk, Joseph R., Jandrot-Perrus, Martine, Neeves, Keith B.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5920765/
https://ncbi.nlm.nih.gov/pubmed/29472230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.118.310731
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