Interleukin‐12 Augments the Generation of Autologous Tumor‐reactive CD8(+) Cytotoxic T Lymphocytes from Tumor‐infiltrating Lymphocytes

Human tumor‐infiltrating lymphocytes (TIL) were obtained from breast cancer, renal cancer or neuroblastoma to investigate the generation of autologous tumor‐reactive CD8(+) cytotoxic T lymphocytes (CTL). When TIL were cultured with interleukin (IL)‐2 (100 U/ml), the growth of TIL peaked around 8–10...

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Bibliographic Details
Published in:Jpn J Cancer Res
Main Authors: Kuge, Soichi, Watanabe, Kazuhito, Makino, Koji, Tokuda, Yutaka, Mitomi, Toshio, Kawamura, Nobuo, Habu, Sonoko, Nishimura, and Takashi
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 1995
Subjects:
Rapid Communication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5920748/
https://ncbi.nlm.nih.gov/pubmed/7730135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1995.tb03030.x
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