Cancer-cell-secreted exosomal miR-105 promotes tumour growth through the MYC-dependent metabolic reprogramming of stromal cells

Cancer and other cells residing in the same niche engage various modes of interactions to synchronize and to buffer the negative effects of environmental changes. Extracellular miRNAs have been recently implicated in the intercellular crosstalk. Here we show a mechanistic model involving breast-canc...

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Udgivet i:Nat Cell Biol
Main Authors: Yan, Wei, Wu, Xiwei, Zhou, Weiying, Fong, Miranda Y., Cao, Minghui, Liu, Juan, Liu, Xiaojing, Chen, Chih-Hong, Fadare, Oluwole, Pizzo, Donald P., Wu, Jiawen, Liu, Liang, Liu, Xuxiang, Chin, Andrew R., Ren, Xiubao, Chen, Yuan, Locasale, Jason W., Wang, Shizhen Emily
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5920728/
https://ncbi.nlm.nih.gov/pubmed/29662176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-018-0083-6
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