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Genetic identification of leptin neural circuits in energy and glucose homeostases

Leptin, a hormone produced in white adipose tissue, acts in the brain to communicate fuel status, suppress appetite following a meal, promote energy expenditure, and maintain blood glucose stability(1,2). Dysregulations of leptin or its receptors (LepR) result in severe obesity and diabetes(3–5). Al...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Xu, Jie, Bartolome, Christopher L., Low, Cho Shing, Yi, Xinchi, Chien, Cheng-Hao, Wang, Peng, Kong, Dong
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5920723/
https://ncbi.nlm.nih.gov/pubmed/29670283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-018-0049-7
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