A Protective Role of Microsomal Prostaglandin E Synthase-1 Derived PGE(2) and the Endothelial EP4 Receptor in Vascular Responses to Injury

OBJECTIVE: Deletion of microsomal (m) prostaglandin (PG) E synthase (S)-1, an anti-inflammatory target alternative to cyclooxygenase-2, attenuates injury-induced neointima formation in mice. This is attributable to the augmented levels of PGI(2), a known restraint of the vascular response to injury,...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Hao, Huifeng, Hu, Sheng, Wan, Qing, Xu, Chuansheng, Chen, Hong, Zhu, Liyuan, Xu, Zhenyu, Meng, Jian, Breyer, Richard M., Li, Nailin, Liu, De-Pei, FitzGerald, Garret A., Wang, Miao
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5920701/
https://ncbi.nlm.nih.gov/pubmed/29599139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.118.310713
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