Knockdown of survivin results in inhibition of epithelial to mesenchymal transition in retinal pigment epithelial cells by attenuating the TGFβ pathway

Proliferative vitreoretinopathy (PVR) is a common complication of open globe injury and the most common cause of failed retinal detachment surgery. The response by retinal pigment epithelial (RPE) cells liberated into the vitreous includes proliferation and migration; most importantly, epithelial to...

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Veröffentlicht in:Biochem Biophys Res Commun
Hauptverfasser: Zhang, Peng, Zhao, Guannan, Ji, Liang, Yin, Jinggang, Lu, Lu, Li, Wei, Zhou, Guomin, Chaum, Edward, Yue, Junming
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5920696/
https://ncbi.nlm.nih.gov/pubmed/29522718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2018.03.021
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