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Absence of ras Mutations and Low Incidence of p53 Mutations in Renal Cell Carcinomas Induced by Ferric Nitrilotriacetate

Renal cell carcinomas induced in male Wistar rats by iron chelate of nitrilotriacetate (Fe‐NTA) were examined for mutations in ras oncogenes and p53 tumor suppressor gene. Fourteen primary tumors and two metastatic tumors from 11 animals were evaluated. Exons 1 and 2 of the H‐, K‐, and N‐ras genes w...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Akiyama, Takashi, Hamazaki, Shuji, Okada, Shigeru
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5920661/
https://ncbi.nlm.nih.gov/pubmed/8636002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1995.tb03307.x
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