Protective Effects of Kampo Medicines and Baicalin against Intestinal Toxicity of a New Anticancer Camptothecin Derivative, Irinotecan Hydrochloride (CPT‐11), in Rats

In clinical use, irinotecan hydrochloride (CPT‐11; 7‐ethyl‐10‐[4‐(piperidmo)‐l‐piperidino]carbonyl‐oxycamptothecin), a novel antitumor agent, causes a relatively high incidence of severe forms of diarrhea. We investigated whether baicalin, an inhibitor of β‐glucuronidase, which deconjugates the gluc...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Takasuna, Kiyoshi, Kasai, Yoshio, Kitano, Yutaka, Mori, Kazuhiko, Kobayashi, Reiko, Hagiwara, Takehiro, Kakihata, Kohji, Hirohashi, Masaaki, Nomura, Mamoru, Nagai, Eiichi, Kamataki, Tetsuya
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 1995
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5920598/
https://ncbi.nlm.nih.gov/pubmed/7493918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1995.tb03010.x
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados