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Clot stability as a determinant of effective factor VIII replacement in hemophilia A

ESSENTIALS: Factor VIII (FVIII) replacement in hemophilia A corrects bleeding due to low thrombin generation. There is uncertainty about the minimal or trough level of FVIII needed for optimal treatment. FVIII improves physical properties of hemophilia clots, including stiffness and permeability. Fi...

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Dades bibliogràfiques
Publicat a:Res Pract Thromb Haemost
Autors principals: Leong, Lilley, Chernysh, Irina N., Xu, Yifan, Sim, Derek, Nagaswami, Chandrasekaran, de Lange, Zelda, Kosolapova, Sofia, Cuker, Adam, Kauser, Katalin, Weisel, John W.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5920517/
https://ncbi.nlm.nih.gov/pubmed/29713693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/rth2.12034
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