Clot stability as a determinant of effective factor VIII replacement in hemophilia A

ESSENTIALS: Factor VIII (FVIII) replacement in hemophilia A corrects bleeding due to low thrombin generation. There is uncertainty about the minimal or trough level of FVIII needed for optimal treatment. FVIII improves physical properties of hemophilia clots, including stiffness and permeability. Fi...

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Detalhes bibliográficos
Publicado no:Res Pract Thromb Haemost
Main Authors: Leong, Lilley, Chernysh, Irina N., Xu, Yifan, Sim, Derek, Nagaswami, Chandrasekaran, de Lange, Zelda, Kosolapova, Sofia, Cuker, Adam, Kauser, Katalin, Weisel, John W.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Original Articles: Haemostasis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5920517/
https://ncbi.nlm.nih.gov/pubmed/29713693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/rth2.12034
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