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The enhanced delivery of salinomycin to CD133(+) ovarian cancer stem cells through CD133 antibody conjugation with poly(lactic-co-glycolic acid)-poly(ethylene glycol) nanoparticles

Ovarian cancer is the most lethal gynecologic malignancy, and ovarian cancer stem cells (CSCs) serve a pivotal function in the metastasis and recurrence of ovarian cancer. Multiple previous studies have validated CD133 as a marker of ovarian CSCs. Although salinomycin is a promising therapeutic agen...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Mi, Yi, Huang, Yuqin, Deng, Jie
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5920508/
https://ncbi.nlm.nih.gov/pubmed/29725407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2018.8140
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