Tamoxifen-Poly(ethylene glycol)-Thiol Gold Nanoparticle Conjugates: Enhanced Potency and Selective Delivery for Breast Cancer Treatment

The breast cancer treatment drug tamoxifen has been widely administered for more than three decades. This small molecule competes with 17β-estradiol for binding to estrogen receptor, a hormone receptor upregulated in a majority of breast cancers, subsequently initiating programmed cell death. We hav...

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Huvudupphovsmän: Dreaden, Erik C., Mwakwari, Sandra C., Sodji, Quaovi H., Oyelere, Adegboyega K., El-Sayed, Mostafa A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2009
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2839930/
https://ncbi.nlm.nih.gov/pubmed/19919059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc9002212
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