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Spatial separation between replisome‐ and template‐induced replication stress signaling
Polymerase‐blocking DNA lesions are thought to elicit a checkpoint response via accumulation of single‐stranded DNA at stalled replication forks. However, as an alternative to persistent fork stalling, re‐priming downstream of lesions can give rise to daughter‐strand gaps behind replication forks. W...
Guardat en:
| Publicat a: | EMBO J |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
John Wiley and Sons Inc.
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5920239/ https://ncbi.nlm.nih.gov/pubmed/29581097 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201798369 |
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