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Ubiquitin-dependent DNA damage bypass is separable from genome replication
Postreplication repair (PRR) is a pathway that allows cells to bypass or overcome lesions during DNA replication1. In eukaryotes, damage bypass is activated by ubiquitylation of the replication clamp PCNA through components of the RAD6 pathway2. Whereas monoubiquitylation of PCNA allows mutagenic tr...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2888004/ https://ncbi.nlm.nih.gov/pubmed/20453836 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09097 |
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