5-aminoisoquinoline improves renal function and fibrosis during recovery phase of cisplatin-induced acute kidney injury in rats

The aim of the present study is to analyze the effects of 5-aminoisoquinoline (5-AIQ), a poly(ADP-ribose) polymerase-1 (PARP1) inhibitor, over renal dysfunction and fibrosis during recovery phase of cisplatin (CisPt)-induced acute kidney injury (AKI) in rats. Male Wistar rats were distributed in thr...

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Publicat a:Biosci Rep
Autors principals: Quesada, Andrés, O’Valle, Francisco, Montoro-Molina, Sebastián, Gómez-Morales, Mercedes, Caba-Molina, Mercedes, González, Juan Francisco, de Gracia, María C., Osuna, Antonio, Vargas, Félix, Wangensteen, Rosemary
Format: Artigo
Idioma:Inglês
Publicat: Portland Press Ltd. 2018
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5920139/
https://ncbi.nlm.nih.gov/pubmed/29599129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20171313
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