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Urinary Aminopeptidase Activities as Early and Predictive Biomarkers of Renal Dysfunction in Cisplatin-Treated Rats

This study analyzes the fluorimetric determination of alanyl- (Ala), glutamyl- (Glu), leucyl-cystinyl- (Cys) and aspartyl-aminopeptidase (AspAp) urinary enzymatic activities as early and predictive biomarkers of renal dysfunction in cisplatin-treated rats. Male Wistar rats (n = 8 each group) receive...

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Detalhes bibliográficos
Main Authors: Quesada, Andrés, Vargas, Félix, Montoro-Molina, Sebastián, O'Valle, Francisco, Rodríguez-Martínez, María Dolores, Osuna, Antonio, Prieto, Isabel, Ramírez, Manuel, Wangensteen, Rosemary
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390365/
https://ncbi.nlm.nih.gov/pubmed/22792302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040402
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