Skin infection boosts memory B-cells specific for a cryptic vaccine epitope of group A streptococcus and broadens the immune response to enhance vaccine efficacy

Antigenic diversity of the M protein is a major constraint to the development of immunity to group A streptococcus (GAS). We demonstrate that a conserved cryptic epitope that is unrecognized by the host immune system following infection can protect mice following vaccination, and that immunity is st...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:NPJ Vaccines
Asıl Yazarlar: Pandey, Manisha, Ozberk, Victoria, Langshaw, Emma L., Calcutt, Ainslie, Powell, Jessica, Batzloff, Michael R., Rivera-Hernandez, Tania, Good, Michael F.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2018
Konular:
Brief Communication
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5920117/
https://ncbi.nlm.nih.gov/pubmed/29736269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41541-018-0053-9
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller