Mutational profiling can identify laryngeal dysplasia at risk of progression to invasive carcinoma

Early diagnosis of laryngeal squamous cell carcinoma (LSCC) at the stage of dysplasia could greatly improve the outcome of affected patients. For the first time we compared the mutational landscape of non-progressing dysplasia (NPD; n = 42) with progressing dysplasia (PD; n = 24), along with patient...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Manterola, Lorea, Aguirre, Pablo, Larrea, Erika, Arestín, María, Gaafar, Ayman, Elorriaga, Kepa, Goicoechea, Ibai, Armesto, María, Fernández-Mercado, Marta, Zabalza, Ignacio, López-Duque, Juan Carlos, Larruskain, Ekhiñe, Sistiaga, Jon Alexander, Landa, Mikel, Zabala, Aitor, Santaolalla, Francisco, Municio, José Antonio, Ispizua, Ángel, García-Pedrero, Juana María, Rodrigo, Juan Pablo, Lawrie, Charles Henderson
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5919930/
https://ncbi.nlm.nih.gov/pubmed/29700339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-24780-7
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