Mutational profiling can identify laryngeal dysplasia at risk of progression to invasive carcinoma

Early diagnosis of laryngeal squamous cell carcinoma (LSCC) at the stage of dysplasia could greatly improve the outcome of affected patients. For the first time we compared the mutational landscape of non-progressing dysplasia (NPD; n = 42) with progressing dysplasia (PD; n = 24), along with patient...

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Publicat a:Sci Rep
Autors principals: Manterola, Lorea, Aguirre, Pablo, Larrea, Erika, Arestín, María, Gaafar, Ayman, Elorriaga, Kepa, Goicoechea, Ibai, Armesto, María, Fernández-Mercado, Marta, Zabalza, Ignacio, López-Duque, Juan Carlos, Larruskain, Ekhiñe, Sistiaga, Jon Alexander, Landa, Mikel, Zabala, Aitor, Santaolalla, Francisco, Municio, José Antonio, Ispizua, Ángel, García-Pedrero, Juana María, Rodrigo, Juan Pablo, Lawrie, Charles Henderson
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5919930/
https://ncbi.nlm.nih.gov/pubmed/29700339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-24780-7
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