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β-Catenin–mediated immune evasion pathway frequently operates in primary cutaneous melanomas

Immunotherapy prolongs survival in only a subset of melanoma patients, highlighting the need to better understand the driver tumor microenvironment. We conducted bioinformatic analyses of 703 transcriptomes to probe the immune landscape of primary cutaneous melanomas in a population-ascertained coho...

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發表在:J Clin Invest
Main Authors: Nsengimana, Jérémie, Laye, Jon, Filia, Anastasia, O’Shea, Sally, Muralidhar, Sathya, Poźniak, Joanna, Droop, Alastair, Chan, May, Walker, Christy, Parkinson, Louise, Gascoyne, Joanne, Mell, Tracey, Polso, Minttu, Jewell, Rosalyn, Randerson-Moor, Juliette, Cook, Graham P., Bishop, D. Timothy, Newton-Bishop, Julia
格式: Artigo
語言:Inglês
出版: American Society for Clinical Investigation 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5919828/
https://ncbi.nlm.nih.gov/pubmed/29664013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI95351
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