β-Catenin–mediated immune evasion pathway frequently operates in primary cutaneous melanomas

Immunotherapy prolongs survival in only a subset of melanoma patients, highlighting the need to better understand the driver tumor microenvironment. We conducted bioinformatic analyses of 703 transcriptomes to probe the immune landscape of primary cutaneous melanomas in a population-ascertained coho...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Clin Invest
Hlavní autoři: Nsengimana, Jérémie, Laye, Jon, Filia, Anastasia, O’Shea, Sally, Muralidhar, Sathya, Poźniak, Joanna, Droop, Alastair, Chan, May, Walker, Christy, Parkinson, Louise, Gascoyne, Joanne, Mell, Tracey, Polso, Minttu, Jewell, Rosalyn, Randerson-Moor, Juliette, Cook, Graham P., Bishop, D. Timothy, Newton-Bishop, Julia
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2018
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5919828/
https://ncbi.nlm.nih.gov/pubmed/29664013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI95351
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky