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Classical IL-6 signaling: a promising therapeutic target for pulmonary arterial hypertension

Current therapies for pulmonary arterial hypertension (PAH) provide symptomatic relief and improve prognosis but fall short of improving long-term survival. There is emerging evidence for a role of inflammatory mediators, primarily IL-6, in the pathogenesis of PAH. However, the mechanisms by which I...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Autores principales: Pullamsetti, Soni Savai, Seeger, Werner, Savai, Rajkumar
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5919797/
https://ncbi.nlm.nih.gov/pubmed/29629898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI120415
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