Bayesian Diallel Analysis Reveals Mx1-Dependent and Mx1-Independent Effects on Response to Influenza A Virus in Mice

Influenza A virus (IAV) is a respiratory pathogen that causes substantial morbidity and mortality during both seasonal and pandemic outbreaks. Infection outcomes in unexposed populations are affected by host genetics, but the host genetic architecture is not well understood. Here, we obtain a broad...

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Detalhes bibliográficos
Publicado no:G3 (Bethesda)
Main Authors: Maurizio, Paul L., Ferris, Martin T., Keele, Gregory R., Miller, Darla R., Shaw, Ginger D., Whitmore, Alan C., West, Ande, Morrison, Clayton R., Noll, Kelsey E., Plante, Kenneth S., Cockrell, Adam S., Threadgill, David W., Pardo-Manuel de Villena, Fernando, Baric, Ralph S., Heise, Mark T., Valdar, William
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2017
Assuntos:
Multiparental Populations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5919740/
https://ncbi.nlm.nih.gov/pubmed/29187420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.117.300438
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