Close Correlation between the Dephosphorylation of p53 and Growth Suppression by Transforming Growth Factor‐β1 in Nasopharyngeal Carcinoma Cells Transduced with Adenovirus Early Region Genes

The mechanism of growth inhibition by transforming growth factor (TGF)‐β1 was investigated. We examined the growth inhibitory effects of TGF‐β1 on human nasopharyngeal carcinoma (KB) cells which constitutively expressed p53. TGF‐β1 suppressed the DNA synthesis of KB cells in a dose‐dependent manner....

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Bibliographic Details
Published in:Jpn J Cancer Res
Main Authors: Mogi, Yoshihiro, Kato, Junji, Horimoto, Masayoshi, Takimoto, Rishu, Murakami, Tsuzuku, Hirayama, Atsushi, Kohgo, Yutaka, Watanabe, Naoki, Niitsu, Yoshiro
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 1994
Subjects:
Rapid Communication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5919502/
https://ncbi.nlm.nih.gov/pubmed/8014102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1994.tb02380.x
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