Kinetics of Internalization and Cytotoxicity of Transferrin‐Neocarzinostatin Conjugate in Human Leukemia Cell Line, K562

Human serum transferrin was conjugated with an anticancer‐active polypeptide, neocarzinostatin, by using N‐succinimidy1‐3‐(2‐pyridyldithio)propionate. The conjugate consisted of 1.8 mol of neocarzinostatin per 1 mol of transferrin on average and retained cytotoxic activity against human tumor cells....

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Detaylı Bibliyografya
Yayımlandı:Jpn J Cancer Res
Asıl Yazarlar: Kohgo, Yutaka, Kondo, Hitoshi, Kato, Junji, Sasaki, Katsunori, Tsushima, Nobuyasu, Nishisato, Takuji, Hirayama, Michiaki, Fujikawa, Koshi, Shintani, Naoaki, Mogi, Yoshihiro, Niitsu, Yoshiro
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Blackwell Publishing Ltd 1990
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5917957/
https://ncbi.nlm.nih.gov/pubmed/2139019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1990.tb02512.x
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