Clonal Analysis of Multiple Point Mutations in the N‐ras Gene in Patients with Acute Myeloid Leukemia

We have screened mutations of the N‐ras gene at codons 12, 13, and 61 in leukemia cells obtained from 100 patients with acute myeloid leukemia (AMD, and found mutated N‐ras alleles in 9 patients. We further analyzed the polyclonality of multiple N‐ras gene mutations in 4 AML patients. One patient, w...

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Bibliographic Details
Published in:Jpn J Cancer Res
Main Authors: Kubo, Kazuaki, Naoe, Tomoki, Kiyoi, Hitoshi, Fukutani, Hisashi, Kato, Yoshiro, Oguri, Takashi, Yamamori, Shunji, Akatsuka, Yoshiki, Kodera, Yoshihisa, Ohno, Ryuzo
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 1993
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5919305/
https://ncbi.nlm.nih.gov/pubmed/8514604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1993.tb00147.x
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