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DANUBE: Data-driven meta-ANalysis using UnBiased Empirical distributions—applied to biological pathway analysis

Identifying the pathways and mechanisms that are significantly impacted in a given phenotype is challenging. Issues include patient heterogeneity and noise. Many experiments do not have a large enough sample size to achieve the statistical power necessary to identify significantly impacted pathways....

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Detalhes bibliográficos
Publicado no:Proc IEEE Inst Electr Electron Eng
Main Authors: Nguyen, Tin, Mitrea, Cristina, Tagett, Rebecca, Draghici, Sorin
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5919277/
https://ncbi.nlm.nih.gov/pubmed/29706661
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