Enhanced Antitumor Effect of Recombinant Human Tumor Necrosis Factor in Combination with Recombinant Human Granulocyte Colony‐stimulating Factor in BALB/c Mice

The synergistic antitumor effect of tumor necrosis factor (TNF) and granulocyte colony‐stimulating factor (G‐CSF) was investigated. G‐CSF was administered subcutaneously to BALB/c mice inoculated with Meth‐A cells at a dose of 2.5 μg/day for 5 consecutive days. When TNF (1 × 10(3) U) was administere...

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Bibliographic Details
Published in:Jpn J Cancer Res
Main Authors: Maeda, Masahiro, Watanabe, Naoki, Tsuji, Naoki, Tsuji, Yasushi, Okamoto, Tetsuro, Sasaki, Hiroyoshi, Akiyama, Shinichiro, Niitsu, Yoshiro
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 1993
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5919274/
https://ncbi.nlm.nih.gov/pubmed/7691787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1993.tb02067.x
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