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Enhancement of Lysosomal Enzyme Activity by Recombinant Human Tumor Necrosis Factor and Its Role in Tumor Cell Killing in vitro

We investigated the effect of recombinant human tumor necrosis factor (TNF) on the lysosomal enzyme activity of various established cell lines in vitro. Incubation of 1 × 10(6)TNF‐sensitive mouse tumorigenic fibroblasts (L‐M cells) in the presence of TNF (100 U/ml) for 48 h increased the total (the...

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Bibliografiske detaljer
Udgivet i:Jpn J Cancer Res
Main Authors: Watanabe, Naoki, Yamauchi, Naofumi, Neda, Hiroshi, Maeda, Masahiro, Tsuji, Yasushi, Okamoto, Tetsuro, Akiyama, Shinichiro, Sasaki, Hiroyoshi, Tsuji, Naoki, Niitsu, Yoshiro
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 1992
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5918887/
https://ncbi.nlm.nih.gov/pubmed/1644666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1992.tb00137.x
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