Limited immune surveillance in lymphoid tissue by cytolytic CD4+ T cells during health and HIV disease

CD4+ T cells subsets have a wide range of important helper and regulatory functions in the immune system. Several studies have specifically suggested that circulating effector CD4+ T cells may play a direct role in control of HIV replication through cytolytic activity or autocrine β-chemokine produc...

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Pubblicato in:PLoS Pathog
Autori principali: Buggert, Marcus, Nguyen, Son, McLane, Laura M., Steblyanko, Maria, Anikeeva, Nadia, Paquin-Proulx, Dominic, Del Rio Estrada, Perla M., Ablanedo-Terrazas, Yuria, Noyan, Kajsa, Reuter, Morgan A., Demers, Korey, Sandberg, Johan K., Eller, Michael A., Streeck, Hendrik, Jansson, Marianne, Nowak, Piotr, Sönnerborg, Anders, Canaday, David H., Naji, Ali, Wherry, E. John, Robb, Merlin L., Deeks, Steven G., Reyes-Teran, Gustavo, Sykulev, Yuri, Karlsson, Annika C., Betts, Michael R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2018
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5919077/
https://ncbi.nlm.nih.gov/pubmed/29652923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006973
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