Limited immune surveillance in lymphoid tissue by cytolytic CD4+ T cells during health and HIV disease

CD4+ T cells subsets have a wide range of important helper and regulatory functions in the immune system. Several studies have specifically suggested that circulating effector CD4+ T cells may play a direct role in control of HIV replication through cytolytic activity or autocrine β-chemokine produc...

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Udgivet i:PLoS Pathog
Main Authors: Buggert, Marcus, Nguyen, Son, McLane, Laura M., Steblyanko, Maria, Anikeeva, Nadia, Paquin-Proulx, Dominic, Del Rio Estrada, Perla M., Ablanedo-Terrazas, Yuria, Noyan, Kajsa, Reuter, Morgan A., Demers, Korey, Sandberg, Johan K., Eller, Michael A., Streeck, Hendrik, Jansson, Marianne, Nowak, Piotr, Sönnerborg, Anders, Canaday, David H., Naji, Ali, Wherry, E. John, Robb, Merlin L., Deeks, Steven G., Reyes-Teran, Gustavo, Sykulev, Yuri, Karlsson, Annika C., Betts, Michael R.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5919077/
https://ncbi.nlm.nih.gov/pubmed/29652923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006973
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