One-carbon metabolism biomarkers and genetic variants in relation to colorectal cancer risk by KRAS and BRAF mutation status

Disturbances in one-carbon metabolism, intracellular reactions involved in nucleotide synthesis and methylation, likely increase the risk of colorectal cancer (CRC). However, results have been inconsistent. To explore whether this inconsistency could be explained by intertumoral heterogeneity, we ev...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Myte, Robin, Gylling, Björn, Häggström, Jenny, Schneede, Jörn, Löfgren-Burström, Anna, Huyghe, Jeroen R., Hallmans, Göran, Meyer, Klaus, Johansson, Ingegerd, Ueland, Per Magne, Palmqvist, Richard, Van Guelpen, Bethany
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2018
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5919009/
https://ncbi.nlm.nih.gov/pubmed/29694444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0196233
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