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One-carbon metabolism biomarkers and genetic variants in relation to colorectal cancer risk by KRAS and BRAF mutation status

Disturbances in one-carbon metabolism, intracellular reactions involved in nucleotide synthesis and methylation, likely increase the risk of colorectal cancer (CRC). However, results have been inconsistent. To explore whether this inconsistency could be explained by intertumoral heterogeneity, we ev...

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Publicat a:PLoS One
Autors principals: Myte, Robin, Gylling, Björn, Häggström, Jenny, Schneede, Jörn, Löfgren-Burström, Anna, Huyghe, Jeroen R., Hallmans, Göran, Meyer, Klaus, Johansson, Ingegerd, Ueland, Per Magne, Palmqvist, Richard, Van Guelpen, Bethany
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5919009/
https://ncbi.nlm.nih.gov/pubmed/29694444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0196233
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