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VLA‐4 Molecules on Tumor Cells Initiate an Adhesive Interaction with VCAM‐1 Molecules on Endothelial Cell Surface
To elucidate the role of VLA‐4 (α4β1 integrin) in tumor metastasis, we have transfected cDNA coding z4 subunit into human flbrosarcoma (HT1080) cells. VLA‐4‐overexpressing HT‐VC1 cells exhibited increased ability to interact with known ligands for VLA‐4, such as CS1 peptide and VCAM‐1 (vascular cell...
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| Опубликовано в: : | Jpn J Cancer Res |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Blackwell Publishing Ltd
1992
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5918735/ https://ncbi.nlm.nih.gov/pubmed/1282907 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1992.tb02763.x |
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