VLA‐4 Molecules on Tumor Cells Initiate an Adhesive Interaction with VCAM‐1 Molecules on Endothelial Cell Surface

To elucidate the role of VLA‐4 (α4β1 integrin) in tumor metastasis, we have transfected cDNA coding z4 subunit into human flbrosarcoma (HT1080) cells. VLA‐4‐overexpressing HT‐VC1 cells exhibited increased ability to interact with known ligands for VLA‐4, such as CS1 peptide and VCAM‐1 (vascular cell...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Kawaguchi, Satoshi, Kikuchi, Kokichi, Ishii, Seiichi, Takada, Yoshikazu, Kobayashi, Seiichi, Uede, Toshimitsu
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 1992
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5918735/
https://ncbi.nlm.nih.gov/pubmed/1282907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1992.tb02763.x
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