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Frequent Occurrence of p53 Gene Mutations in Uterine Cancers at Advanced Clinical Stage and with Aggressive Histological Phenotypes

The clinical and pathological significance of mutation of the p53 tumor‐suppressor gene was examined in 108 cases of primary uterine cancers using single‐strand conformation polymorphism and direct DNA sequencing analyses. Mutation of the p53 gene was detected in 19 (31%) of 62 cases of cancer of th...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Jpn J Cancer Res
Hauptverfasser: Tsuda, Hitoshi, Hirohashi, Setsuo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Publishing Ltd 1992
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5918705/
https://ncbi.nlm.nih.gov/pubmed/1336492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1992.tb02743.x
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