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In silico investigation of lavandulyl flavonoids for the development of potent fatty acid synthase-inhibitory prototypes

BACKGROUND: Inhibition of fatty acid synthase (FAS) is regarded as a sensible therapeutic strategy for the development of optimal anti-cancer agents. Flavonoids exhibit potent anti-neoplastic properties. METHODS: The MeOH extract of Sophora flavescens was subjected to chromatographic analyses such a...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta
Main Authors: Oh, Joonseok, Liu, Haining, Park, Hyun Bong, Ferreira, Daneel, Jeong, Gil-Saeng, Hamann, Mark T., Doerksen, Robert J., Na, MinKyun
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5918680/
https://ncbi.nlm.nih.gov/pubmed/27531709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2016.08.001
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