MafA-Controlled Nicotinic Receptor Expression Is Essential for Insulin Secretion and Is Impaired in Patients with Type 2 Diabetes

Monoamine and acetylcholine neurotransmitters from the autonomic nervous system (ANS) regulate insulin secretion in pancreatic islets. The molecular mechanisms controlling neurotransmitter signaling in islet β cells and their impact on diabetes development are only partially understood. Using a gluc...

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Gepubliceerd in:Cell Rep
Hoofdauteurs: Ganic, Elvira, Singh, Tania, Luan, Cheng, Fadista, João, Johansson, Jenny K., Cyphert, Holly Ann, Bennet, Hedvig, Storm, Petter, Prost, Gaëlle, Ahlenius, Henrik, Renström, Erik, Stein, Roland, Groop, Leif, Fex, Malin, Artner, Isabella
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5918632/
https://ncbi.nlm.nih.gov/pubmed/26904947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.02.002
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