FOXP3 Mutations Causing Early-Onset Insulin-Requiring Diabetes but Without Other Features of IPEX Syndrome: FOXP3 mutations with IPEX-like Diabetes

Diabetes occurs in 1/90,000–1/160,000 births and when diagnosed under 6 months of age is very likely to have a primary genetic cause. FOXP3 encodes a transcription factor critical for T regulatory cell function and mutations are known to cause “Immune dysregulation, Polyendocrinopathy (including ins...

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Bibliographic Details
Published in:Pediatr Diabetes
Main Authors: Hwang, Jessica L., Park, Soo-Young, Ye, Honggang, Sanyoura, May, Pastore, Ashley N., Carmody, David, del Gaudio, Daniela, Wilson, Janna F., Hanis, Craig L., Liu, Xiaoming, Atzmon, Gil, Glaser, Benjamin, Philipson, Louis H., Greeley, Siri Atma W.
Format: Artigo
Language:Inglês
Published: 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5918222/
https://ncbi.nlm.nih.gov/pubmed/29193502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/pedi.12612
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