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Early Intensive Insulin Use May Preserve β-Cell Function in Neonatal Diabetes Due to Mutations in the Proinsulin Gene

Although mutations in the proinsulin gene (INS) are the second most common cause of neonatal diabetes mellitus, the natural history of β-cell death and the most appropriate treatments remains unknown. We describe the management and outcome of two sisters with INS-mediated diabetes (S1 and S2) and su...

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發表在:J Endocr Soc
Main Authors: Letourneau, Lisa R., Carmody, David, Philipson, Louis H., Greeley, Siri Atma W.
格式: Artigo
語言:Inglês
出版: Endocrine Society 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5738118/
https://ncbi.nlm.nih.gov/pubmed/29308449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2017-00356
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