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Early Intensive Insulin Use May Preserve β-Cell Function in Neonatal Diabetes Due to Mutations in the Proinsulin Gene

Although mutations in the proinsulin gene (INS) are the second most common cause of neonatal diabetes mellitus, the natural history of β-cell death and the most appropriate treatments remains unknown. We describe the management and outcome of two sisters with INS-mediated diabetes (S1 and S2) and su...

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Detalhes bibliográficos
Publicado no:J Endocr Soc
Main Authors: Letourneau, Lisa R., Carmody, David, Philipson, Louis H., Greeley, Siri Atma W.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5738118/
https://ncbi.nlm.nih.gov/pubmed/29308449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2017-00356
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